Intrathecal Delivery
Intrathecal delivery means giving a therapy into the cerebrospinal fluid, usually through a lumbar puncture or a device, so it can reach the central nervous system more directly. This route is used or studied for some neurological diseases because the blood-brain barrier can prevent many medicines from reaching the brain and spinal cord after ordinary blood-based dosing.
Why it matters
Many rare diseases affect the nervous system. Understanding intrathecal delivery helps families ask practical questions about procedure burden, repeat dosing, safety, anesthesia, and whether the therapy reaches the right tissues.
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